Commiphora wightii, with common names Indian bdellium-tree, jugal, or Mukul myrrh tree, is a flowering plant in the family Burseraceae, which produces a fragrant resin called gugal, guggul or guggul, that is used in incense and Vedic medicine (or ayurveda). Commiphora wightii has been a key component in the ancient Indian Ayurvedic system of medicine.
The extract of gum guggul, called guggulipid, guggulipid, or guggulipid, has been used in Unani and Ayurvedic medicine, for nearly 3,000 years in India. One chemical ingredient in the extract is the steroid guggulsterone, which acts as an antagonist of the farnesoid X receptor, once believed to decrease cholesterol synthesis in the liver. However, several studies have been published that indicate no overall reduction in total cholesterol occurs using various dosages of guggulsterone, and levels of low-density lipoprotein (“bad cholesterol”) increased in many people.