Bitter Oleander (underjaw) (Holarrhena antidysenterica) is a deciduous shrub or a small tree, growing up to 3 ms high. The short stem has pale bark and several branches. Oppositely arranges ovate, and obtusely acuminate leaves are 10-20 cm long. Leaf stalks are very short. White flowers appear in corymb-like cymes, 5-15 cm across, at the end of branches. Flowers have five white petals 2-3 cm long which turn creamish yellow as they age. The flowers are beautiful with oblong petals which are rounded at the tip and remind one of frangipani. Indrajao is native to Africa, the Indian Subcontinent of Indo-China. It is also found in the Himalayas up to altitudes of 1500 m. Flowering: April-July.It is a medicinal plant in Ayurveda. One of its botanical synonyms Holarrhena antidysenterica says it all. It is one of the best drugs for Diarrhoea. In chronic diarrhea & to check blood coming from stool, it should be given with Isobgol, caster oil, or Indrayav. According to Ayurveda, the bark is useful in the treatment of piles, skin diseases, and biliousness. The bark is used externally in case of skin troubles. The bark is mostly mixed with cow urine and apply it in affected parts. In the treatment of urinary troubles, the bark is given with cow milk. The fresh juice of bark is considered good to check diarrhea.